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Lateral flow assays towards point-of-care cancer detection: A review of current progress and future trends

2020

Abstract Cancer is one of the main causes of mortality and morbidity worldwide. However, its early non-invasive detection via quantification of appropriate biomarkers can significantly reduce mortality, enhance survival, and save treatment costs. Lateral flow test strips (LFTS) are nowadays considered as the most attractive point-of-care devices for healthcare applications. However, the quantification of cancer biomarkers in body fluids suffers from some challenges including i) the necessity for multiplex analysis, ii) the development of sensitive detection systems, iii) to overcome the analysis of complex samples, at the same time, it should keep the quality assurance criteria for an accur…

business.industryComputer science010401 analytical chemistryCancer detection01 natural sciences0104 chemical sciencesAnalytical ChemistryLateral flow testRisk analysis (engineering)Cancer biomarkersTreatment costsbusinessQuality assuranceSpectroscopyPoint of careTrAC Trends in Analytical Chemistry
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